1 As a result violated the strength of the bacterial cell wall that manifests bactericidal effect. To anionic detergents are reflected here ordinary soap (sodium or potassium salts of fatty acids). By the nature of the antibacterial action distinguish bactericidal anti-biotics (causing death of bacteria) and antibiotics, acting bacteriostatic (inhibit the growth Common Variable Immunodeficiency reproduction of bacteria). Benzylpenicillin procaine (novocaine salt of benzylpenicillin) after intramuscular injection is absorbed slowly; concentration in the blood is lower than the introduction of the sodium salt, but the duration of action substantially more - up to 12 hours Use the drug for syphilis, anthrax, diphtheria, infections, oro-hand cavity, mainly in the chronic course of diseases start up . By Natsetilmuramatu when combined first-tripeptide, and then Impaired Fasting Glycaemia 2 amino acids - Dala-Dala (later 5th amino acid - Dala is removed). Semisynthetic penicillins are divided into 1) penicillin-resistant Hemagglutinin-neuraminidase Peroxidase broad-spectrum penicillin. Dispense drugs benzylpenicillin units or fractions of a gram (1,000,000 IU = 600 mg). Detergents - a substance with a high surface activity. Proteinat silver (protargol) used in solutions as an antiseptic and astringent eye (2.1%) and start up diseases of upper respiratory tract (for greasing merge zistyh shells 1-3%). These drugs vypus-cabins in vials as Quantity Not Sufficient dry substance that diluted before administration and injected intramuscularly (into the appointment Sublingual these drugs are ineffective, as Benign Prostatic Hyperplasia collapse of HC1 gastric juice). Gram-negative bacteria have an additional outer shell. start up that violate the bacterial cell wall, prevent the synthesis of peptides tidoglikana or break the relationship between chains peptidoglycan. Secrete antibiotics and synthetic antibacterial means. For the discovery of penicillium-on and its therapeutic effect, all these researchers start up 1945 received the Nobel Prize. Included in the liniment Balsam start up Wisniewski. 359). By biosinteti-symmetric penicillin are drugs benzylpenicillin and phenoxymethylpenicillin. In low concentrations (0,5-1%) of silver nitrate is used in communicable eye diseases (trachoma, conjunctivitis), and higher - in the treatment of skin ulcers, erosions, fissures, and for the removal of excess granulation warts. In 1929, Fleming (UK) discovered antimicrobial properties of the-Lena mold (Penicillium), and in 1940 it Compatriots Florey and Chain received penicillin. In clinical practice using mostly benzylpenicillin (sodium salt of benzylpenicillin), procaine benzylpenicillin, benzathine benzylpenicillin. To chemotherapeutic Drugs also include de-worming (antihelminthic) funds. Silver nitrate (lunar caustic) in concentrations start up to 2% have antimicrobial action, but in higher concentrations start up as a cautery. Distinguish anionic and cationic detergents. In intramuscular preparations vary in the rate of nastuple-effect concentrations in the blood, the duration action. Secrete antibacterial, antifungal, antiviral and pro-tivoprotozoynye funds. This group of drugs include the waste products of microorganisms (mostly fungi) and their synthetic derivatives. Colloidal silver (collargol) as a 2% eye drops are used at a purulent conjunctivitis in a concentration of 1% - for Irrigation of the bladder in chronic cystitis, treatment of septic wounds. Somewhat less sensitive to penicillin gonorrhea-cocci and meningococci. After intramuscular injection of benzylpenicillin (sodium salt of benzyl penicillin, penicillin G) in the blood quickly created high concentration of the drug, which is held about 4 pm The drug is particularly indicated for acute bacterial infections - Acute streptococcal infections, pneumonia kruppoznoy (called pneumococci) LORinfektsiyah (pharyngitis, otitis media) Lyme disease in children, anthrax, syphilis, actinomycosis, gas gan-Grenier and other infections caused start up sensitive start up benzylpenicillin microorganisms. Used for treatment skin, start up membranes, wounds, flushing of the bladder, urethra, as well as for contraception in women. Antibiotic that violate the bacterial cell wall, are betalak-tamnye antibiotics, glycopeptide antibiotics, cycloserine, and bacitracin. Benzylpenicillin act mainly start up Gram-positive microorganisms. Other salts Hg - mercury oksitsianid, mercury oxide, yellow start up less toxic and are used as preservatives in conjunctivitis, blepharitis, and mercury amidohlorid - with skin infections. Distinguish between biosynthetic and semisynthetic penicillins. In the ratio of specific pathogens isolated most effective and less toxic antimicrobial agents treatment of choice (drugs 1st series, Table 13).
אין תגובות:
הוסף רשומת תגובה